本頁所有文獻皆篩選自SJR 期刊評比指標等級 Q1 或 Q2。

SJR 期刊評比指標之數值與排名 (Q1-Q4)
Impact factor : 期刊的影響係數是用來計算某一期刊於某一年被引用之頻率,用以評量該期刊於某一學科領域內之相對重要性,同一學科領堿內,影響指數值越大,表示該期刊之重要性越高。

基於期刊影響指數(impact factor)等因素,SCImago會在每年度為各領域的期刊做排名。
將屬於同領域的期刊分為四等份,期刊影響指數(impact factor)排名從上到下,前25%之期刊,期刊等級表示為Q1,介於25%~50%為Q2,50%~75%為Q3,最後75%後為Q4。

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3% AC. Net + 1% 鋅

Oleanolic acid 降低皮脂分泌,抑制5a-reductase的效果。
Laxminarain Misraa, Hartmut Laatschb (2000). "Triterpenoids, essential oil and photo-oxidative 28 R 13- lactonization of oleanolic acid from Lantana camarap." Phytochemistry54: 969±974.

Nordihydroguaiaretic acid 可以控制皮脂分泌,抑制5a-reductase的效果。
Richard A. Hiipakka, H.-Z. Z., Wei Dai, Qing Dai, Shutsung Liao* (2002). "Structure±activity relationships for inhibition of human 5a-reductases by polyphenols." Biochemical Pharmacology: 1165-1176.

Nordihydroguaiaretic acid 降低皮脂腺過度作用,同時增加水含量。
Kim, H. Y., et al. (2012). "Impact on inflammation and recovery of skin barrier by nordihydroguaiaretic Acid as a protease-activated receptor 2 antagonist." Biomol Ther (Seoul)20(5): 463-469.

鋅離子可以調降皮脂分泌,以及抗發炎效果可以幫助對抗油性肌。
Gupta, M., et al. (2014). "Zinc therapy in dermatology: a review." Dermatol Res Pract2014: 709152.


3% 酯化維他命C (VC-IP)

Ascorbyl Tetraisopalmitate 是穩定的維他命C衍生物,可以在皮膚內有效轉換成維他命C,達到美白功能。
Al-Niaimi, F., & Chiang, N. Y. Z. (2017). Topical vitamin C and the skin: Mechanisms of action and clinical applications. Journal of Clinical and Aesthetic Dermatology, 10, 14–17.
Fernandes, D. and M. Signorini (2008). "Combating photoaging with percutaneous collagen induction." Clin Dermatol26(2): 192-199.

Ascorbyl Tetraisopalmitate 抑制黑色素細胞增生,可以抑制黑色素增生因子IL-1a 和PGE2的分泌。
Ascorbyl Tetraisopalmitate 可以避免受UV照射的肌膚色素沈澱。
Ochiai, Y., et al. (2006). "A new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), prevents UV-induced skin pigmentation through its anti-oxidative properties." Journal of Dermatological Science44(1): 37-44.


Brio (高效眼部胜肽精華)

三肽GHK和銅離子結合後,能刺激膠原蛋白合成,增強肌膚緊實、組織修復。
Lintner, K., Peschard, O. 2000Biologically active peptides: from a laboratory bench curiosity to function skin care productInt. J. Cosmet. Sci.22207218

白楊素藉由清除膽紅素,可以有效減少黑眼圈產生。
Hesperidin methyl chalcone 強化毛細血管,去除眼部周圍腫脹。
雙肽改善淋巴循環,減少眼睛周遭浮腫。
Fathi, R., et al. (2015). "Minimally invasive eyelid care in dermatology: medical, laser, and cosmetic therapies." Clin Dermatol33(2): 207-216.

棕櫚酰三肽-5 增加膠原蛋白生成;研究顯示效果高過棕櫚酰五肽-5 60%,有效增加肌膚彈性。
Bucay, V. W. and D. Day (2013). "Adjunctive skin care of the brow and periorbital region." Clin Plast Surg40(1): 225-236.


2% 维他命A醇衍生物 (HPR) + GABA

研究顯示维他命A醇衍生物(HPR)在相同濃度下,相較於視黃醇(retinol)、視黃醛(retinaldehyde)、棕櫚酸酯(retinyl palmitate)在改善老化方面有更好的效果。
Nora Ruth, M., Estée Lauder Companies; Thomas Mammone, PhD, MBA, Estée Lauder Companies (2018). "Antiaging effects of retinoid hydroxypinacolone retinoate on skin models." Journal of the American Academy of Dermatology 79(3).
Mukherjee S, Date A, Patravale V, et al. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clin Interv Aging 2006;1:327–48.

臨床試驗顯示,使用含有GABA、玻尿酸、N-乙醯葡糖胺的產品60天後,99%的受試者感覺肌膚變光滑,85%的受試者感覺肌膚變緊實,75%的人感覺皺紋減少。
Ferrillo, M., et al. (2018). "Instrumental, clinical and subjective evaluation of the efficacy of a cosmetic treatment for home use." J Cosmet Laser Ther: 1-6.

沒藥醇能改善肌膚發炎,舒緩肌膚。
Rocha NF, Rios ER, Carvalho AM, et al. Anti-nociceptive and anti-inflammatory activities of (􏰁)-a-bisabolol in rodents. Naunyn Schmiedebergs Arch Pharmacol. 2011;384:525-533.


2% 多重玻尿酸 + 1% Na-PCA

玻尿酸含水量可以高達自身體積的1000倍。
Johl SS, Burgett RA. Dermal filler agents: a practical review. Curr Opin Ophthalmol 2006;17(5):471–479

玻尿酸的親水性幫助肌膚的保濕和彈性。

Sylvie Verdier-Sévrain, M. F. d. r. B., PhD2 (2007). "Skin hydration: a review on its molecular mechanisms." Journal of Cosmetic Dermatology6: 75–82.

玻尿酸促進組織保濕,進而對肌膚修復有幫助。

Manuskiatti, W, Maibach, HI. Hyaluronic acid and skin: wound healing and aging. Int J Dermatol. 1996;35:539–544.

低分子量玻尿酸滲透肌膚能力更勝大分子玻尿酸,有深入、抗老效果。
Farwick, M., et al. (2011). "Fifty-kDa Hyaluronic Acid Upregulates Some Epidermal Genes without Changing TNF-α Expression in Reconstituted Epidermis." Skin Pharmacology and Physiology24(4): 210-217.

Na-PCA 幫助肌膚保濕,改善乾燥、鬆弛肌膚問題。
Rawlings AV, Canestrari DA, Dobkowski B. Moisturizer technology versus clinical performance. Dermatol Ther. 2004;17(suppl 1):49-56.


Luz 淡斑美白精華

Potassium 4-methoxysalicylate 能透過抑制酪氨酸酶(酪氨酸酶幫助合成黑色素)達到美白肌膚。

Ito, S. and K. Wakamatsu (2015). "A convenient screening method to differentiate phenolic skin whitening tyrosinase inhibitors from leukoderma-inducing phenols." Journal of Dermatological Science80(1): 18-24.

臨床試驗顯示傳明酸有效減少黑色素和黃褐斑。
Atefi, N., et al. (2017). "Therapeutic Effects of Topical Tranexamic Acid in Comparison with Hydroquinone in Treatment of Women with Melasma." Dermatol Ther (Heidelb)7(3): 417-424.


九胜肽有效抑制黑色素生成,美白肌膚。
Yang, J., et al. (2011). "pH-responsive hydrogel microparticles as intelligent delivery carriers for α-MSH antagonists." AIChE Journal57(7): 1919-1925.



100% 純植物萃取角鯊烷

角鯊烷提供保濕、潤膚效果,穩定性更勝角鯊烯。 
Kim, S.-K. and F. Karadeniz (2012). Biological Importance and Applications of Squalene and Squalane. Marine Medicinal Foods - Implications and Applications - Animals and Microbes: 223-233.

角鯊烷就有潤膚、保濕效果,此外,也有抗氧化、不需要防腐劑。

Ciriminna, R., et al. (2014). "Catalytic Hydrogenation of Squalene to Squalane." Organic Process Research & Development18(9): 1110-1115.


100% 有機冷壓萃取馬魯拉油


馬魯拉油具有相似橄欖油的脂肪酸組成,但有十倍的氧化安定性。
Mariod AA, Abdelwahab SI (2012). Sclerocarya birrea (Marula), an African tree of nutritional and medicinal uses: a review. Food Rev. Int. 28(4):375-388.

馬魯拉油富含棕櫚酸,在皮膚表面產生保護作用,它吸收快速,滋潤肌膚、減少紅斑、減少水分散失,舒緩肌膚。
A. Mariod, B. Matthäus, Y.A. Idris, S. AbdelwahabFatty acids, tocopherols, phenolics and the antimicrobial effect of Sclerocarya birrea kernels with different harvesting dates Journal of the American Oil Chemists Society, 87 (4) (2010), pp. 377-384

馬魯拉油富含不飽和脂肪酸,油酸(70-78%),幫助抗氧化表現。
I. Vermaak, G.P.P. Kamatou, B. Komane-Mofokeng, A.M. Viljoen, K.BeckettAfrican seed oils of commercial importance-cosmetic applications S. Afr. J. Bot., 77 (2011), pp. 920-933

馬魯拉油的氧化穩定性顯著性高於芝麻油、花生油、葵花子油、棉籽油。
Mariod, A.; Matthäus, B.; Eichner, K.; Hussein, I.H. Study of fatty acids, tocopherol, sterols, phenolic compounds and oxidative stability of three unconventional oils in comparison with four conventional ones. Arab J. Food Nutr. 2009, 23, 50–55.


100% 有機冷壓萃取玫瑰果油


玫瑰果油富含多元不飽和脂肪酸,亞油酸(54.05%)、亞麻酸(19.37%)屬於人體必需脂肪酸omega-3和omega-6的範疇。
亞油酸和亞麻酸是表皮的重要構成要素之一,幫助強化肌膚屏障。

Phetcharat, L.; Wongsuphasawat, K.; Winther, K. The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity. Clin. Interv. Aging 2015,10, 1849

玫瑰果油有強的抗氧化能力相比於一般植物油。
Ilyasog ̆lu, H. Characterization of Rosehip (Rosa canina L.) Seed and Seed Oil. Int. J. Food Prop. 2014, 17, 1591–1598.

玫瑰果油有好的抗氧化能力,改善肌膚老化。
Lin T-K, Zhong L, Santiago J. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. Int J Mol Sci. 2017;19(1):70.


10% 維他命B3 + 2% 淡紋四胜肽


臨床試驗顯示菸鹼醯胺有效減少細紋、皺紋、色斑、紅斑,對肌膚彈性也有改善。
Bissett DL, Oblong JE, Berge CA. Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatol Surg 2005; 31: 860–865; Discussion 865.

文獻指出含有菸鹼醯胺的保濕產品能改善角質層的屏障功能。
Draelos ZD, Ertel K, Berge C. Niacinamide-containing facial moisturizer improves skin barrier and benefits subjects with rosacea. Cutis. 2005 76:135–141.

菸鹼醯胺對皮層屏障功能有穩定的效果,能減少肌膚水分散失、改善表面膚質、淡化皺紋、減少色素沈澱。

Gehring W. Nicotinic acid/niacinamide and the skin. J Cosmet Dermatol 2004;3:88–93.

菸鹼醯胺能減少油脂過度分泌,縮小肌膚毛孔、改善肌膚質地。
BissettDL,OblongJE,SaudA,etal.Topicalniacinamideprovidesskin aging appearance benefits while enhancing barrier function. J Clin Dermatol 2003;32S:9-18. Draelos ZD, Matsubara A, Smiles K. The effect of 2% niacinamide on facial sebum production. J Cos Laser Ther 2006;8:96-101.

三肽GHK和銅離子結合後,能刺激膠原蛋白合成,增強肌膚緊實、組織修復。
Lintner, K.,Peschard, O. 2000Biologically active peptides: from a laboratory bench curiosity to function skin care productInt. J. Cosmet. Sci.22207218



甘醇酸(Glycolic acid)

臨床試驗搜集40位亞洲人,結果顯示甘醇酸改善亞洲人丘疹、粉刺。
Wang CM, Huang CL, Hu CT, Chan HL. The effect of glycolic acid on the treatment of acne in Asian skin. Dermatol Surg. 1997;23:23‐29.

甘醇酸可以運用在所以肌膚種類進行換膚,並且少危險性。
Moy, L. S., Murad, H., & Moy, R. L. (1993). Glycolic acid peels for the treatment of wrinkles and photoaging. Journal of Dermatologic Surgery and Oncology,19, 243–246.

對於尋常性痤瘡,30% 甘醇酸煥膚為成功的輔助性治療。
Kessler E, Flanagan K, Chia C et al. Comparison of alpha‐ and beta‐hydroxy acid chemical peels in the treatment of mild to moderately severe facial acne vulgaris. Dermatol Surg2008;34: 45–50; discussion 1.


乳酸(Lactic acid)

乳酸幫助肌膚美白、恢復活力的能力來自於抑制酪氨酸酶的形成。
R.P. John, K.M. Nampoothiri, A. Pandey Fermentative production of lactic acid from biomass: an overview on process developments and future perspectives. Appl Microbiol Biotechnol, 74 (2007), pp. 524-534

乳酸在治療黃褐斑被認為是有效、安全的換膚成份。
Sharquie KE, Al‐Tikreety MM, Al‐Mashhadani SA. Lactic acid chemical peels as a new therapeutic modality in melasma in comparison to Jessner’s solution chemical peels. Dermatol Sur2006; 32: 1429–1436.

乳酸能夠刺激角質層中神經醯胺合成,更新肌膚屏障、抵抗皮膚乾燥。
Rawlings AV, Davies A, Carlomusto M, et al. Effect of lactic acid isomers on keratinocyte ceramide synthesis, stratum corneum lipid levels and stratum corneum barrier function. Arch Dermatol Res. 1996;288(7):383–390.


水楊酸(
Salicylic acid)

水楊酸可以有效調控皮脂分泌、軟化角質。

Arif T. Salicylic acid as a peeling agent: a comprehensive review. Clin Cosmet Investig Dermatol 2015;8:455–61

2%水楊酸和15%甘醇酸所製成的凝膠應用在面部的疣,8週過後,有效改善。
Rodríguez-Cerdeira C, Sánchez-Blanco E. Glycolic acid 15% plus salicylic acid 2%: a new therapeutic pearl for facial flat warts. J Clin Aesthet Dermatol 2011;4:62–64


杏仁酸(Mandelic acid)


杏仁酸能夠降低角質細胞貼附能力,進而達到去角質的效果,杏仁酸為大分子,緩慢穿透肌膚,使肌膚更能夠承受,同時具有抗菌能力。
David E Castillo, Jonette E Keri. Chemical peels in the treatment of acne: patient selection and perspectives. Clin Cosmet Investig Dermatol. 2018; 11: 365–372.

杏仁酸能改善不同種類的暗瘡,包括粉刺、丘疹膿皰、暗瘡。
Kontochristopoulos G, Platsidaki E. Chemical peels in active acne and acne scars. Clin Dermatol. 2017;35(2):179–182.

20%的杏仁酸加上檸檬酸有助於煥膚,改善過油、易於痘痘的肌膚。
Green et al., 2009 B.A. Green, R.J. Yu, E.J. Van ScottClinical and cosmeceutical uses of hydroxyacids. Clinics in Dermatology, 27 (2009), pp. 495-501